Resolvin D1 attenuates mechanical allodynia after burn injury: Involvement of spinal glia, p38 mitogen-activated protein kinase, and brain-derived neurotrophic factor …
X Zhao, X Li, H Guo, P Liu, M Ma, Y Wang - Molecular Pain, 2023 - journals.sagepub.com
… downregulated BDNF/TrkB following burn injury. Furthermore, … might attenuate mechanical
allodynia after burn injury by … that burn injury in rats resulted in hyperalgesia and allodynia …
allodynia after burn injury by … that burn injury in rats resulted in hyperalgesia and allodynia …
Nonopioid GTS-21 mitigates burn injury pain in rats by decreasing spinal cord inflammatory responses
Y Zhou, Y Leung-Pitt, H Deng, Y Ren, Z You… - Anesthesia & …, 2021 - journals.lww.com
… MLA is a specific α7AChR blocker for 1 wk. Preliminary … GTS-21 attenuates postburn
mechanical allodynia in young … GTS-21 attenuated postburn heat hyperalgesia in young rats. A, …
mechanical allodynia in young … GTS-21 attenuated postburn heat hyperalgesia in young rats. A, …
Endogenous analgesic systems and neuropathic pain
E Sokolaj - 2023 - ses.library.usyd.edu.au
… , such as naloxone and naltrexone, attenuate the stress-… by cannabinoid CB1 knockout
and antagonists, such as AM251, … the cannabinoid CB1 receptor antagonist AM281 (3 mg·kg-1) …
and antagonists, such as AM251, … the cannabinoid CB1 receptor antagonist AM281 (3 mg·kg-1) …
… and meta-analysis of cannabinoids, cannabis-based medicines, and endocannabinoid system modulators tested for antinociceptive effects in animal models of injury …
… frequently measured by attenuation of hypersensitivity to … system include selective synthetic
cannabinoid receptor agonists, … allodynia OR neuralgia OR hypersensitivity OR hyperalgesia …
cannabinoid receptor agonists, … allodynia OR neuralgia OR hypersensitivity OR hyperalgesia …
[HTML][HTML] The nonopioid cholinergic agonist GTS-21 mitigates morphine-induced aggravation of burn injury pain together with inhibition of spinal microglia activation in …
Y Ren, Y Zhou, Z You, H Deng, WR Kem, J Mao… - British Journal of …, 2022 - Elsevier
… attenuated by administration of α7AChR agonist, GTS-21. … of thermal hyperalgesia=0.8 and
mechanical allodynia=2.5 … with the α7AchR selective antagonist, methyllycaconitine. Using …
mechanical allodynia=2.5 … with the α7AchR selective antagonist, methyllycaconitine. Using …
Cannabinoid receptor agonists from Conus venoms alleviate pain-related behavior in rats
S Jergova, C Perez, JS Imperial, S Gajavelli… - Pharmacology …, 2021 - Elsevier
… test and attenuated thermal and mechanical allodynia in nerve injury … b) Evaluation of thermal
and mechanical hyperalgesia in CCI … Pretreatment with AM251, a CB1 receptor antagonist, …
and mechanical hyperalgesia in CCI … Pretreatment with AM251, a CB1 receptor antagonist, …
[HTML][HTML] Cannabinoid therapeutics in chronic neuropathic pain: from animal research to human treatment
RMP Campos, AFL Aguiar, Y Paes-Colli… - Frontiers in …, 2021 - frontiersin.org
… On the other hand, AM251, a CB1 antagonist, reversed the effects … hyperalgesia through
the use of Cannabis sp. extract was not affected by the use of cannabinoid receptor antagonists, …
the use of Cannabis sp. extract was not affected by the use of cannabinoid receptor antagonists, …
[HTML][HTML] A type II cannabis extract and a 1: 1 blend of Δ (9)-tetrahydrocannabinol and cannabidiol display distinct antinociceptive profiles and engage different …
B Benredjem, G Pineyro - Frontiers in Pharmacology, 2023 - frontiersin.org
… using CB1 (AM251) and CB2 (AM630) receptor antagonists as … is one of the most common
causes of hyperalgesia, … anti-allodynic responses induced by the different cannabinoids in …
causes of hyperalgesia, … anti-allodynic responses induced by the different cannabinoids in …
[HTML][HTML] Peripheral deficiency and antiallodynic effects of 2-arachidonoyl glycerol in a mouse model of paclitaxel-induced neuropathic pain
… , with cannabinoid type 1 (CB 1 ) receptor antagonist AM251 … coincided with mechanical
allodynia and thermal hyperalgesia. In … cannabinoid receptor agonist could alleviate mechanical …
allodynia and thermal hyperalgesia. In … cannabinoid receptor agonist could alleviate mechanical …
A synergistic analgesic effect of morphine in combination with the CB1 receptor agonist, ACPA, in normal, hypothyroid, and hyperthyroid male rats
MR Zarrindast, F Khakpai - Acta Neurobiologiae Experimentalis, 2023 - ane.pl
… not attenuate hyperalgesia induced by an effective dose of AM251. Co‑injection of ACPA …
and normal rats in response to a CB1 receptor agonist or antagonist, the effect of the CB1 …
and normal rats in response to a CB1 receptor agonist or antagonist, the effect of the CB1 …